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MCP-counter, a software tool allowing to assess the abundance of microenvironment cell populations using gene expresssion

par Aurélien de Reyniès | Sep 14, 2016 | Publication

Developed through a collaboration between the CIT team and Pr Hervé Fridman’s lab, MCP-counter software allows, given a transcriptome profile, to robustly measure the abundance of 10 microenvironment cellular populations (T cells, T CD8 cells, NK cells,...

Integrative molecular analysis of oligodendroglial tumours identifies a new subtype of 1p/19q co-deleted gliomas associated with a more aggressive profile

par Aurelie Kamoun | Avr 21, 2016 | Publication

Oligodendroglial tumours are a subtype of brain tumours accounting for about 10% of gliomas. Most of these tumours share a common genomic alteration – a genomic loss of both chromosomal arms 1p and 19q – but their prognosis remains highly heterogeneous....

The consensus molecular subtypes of colorectal cancer

par Rémy Nicolle | Nov 10, 2015 | Publication

An international consortium of 7 research teams, including the CIT team, just published in Nature Medicine [1] a  consensus classification of colorectal cancers (CRC) based on gene expression data. Based on the analysis of more than 4,000 tumor samples, this work lead...
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