CIT Program Research Cancer Tumeurs Ligue

THE CIT PROGRAM

Launched in 2000 by the French League Against Cancer, the CIT research program aims at characterizing exhaustively the cancer-driving genomic alterations. These abnormalities can be deeply analysed thanks to the development of high-troughput biological techniques and results in a better understanding of the mechanisms driving each cancer type. Our work establishes a strong basis for the development an improvement of precision medicine, with the purpose of proving a clinical care adapted to the genomic characteristics of each tumor.

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CIT Program Cancer Tumeurs Ligue Research

Localized prostate cancer: a molecular signature to identify non-aggressive tumours

Although prostate cancer is the most frequent cancer in men, only 15% of patients will eventually develop a metastatic disease. However, immediate radical surgery (prostatectomy) remains a standard of care for localized prostate tumours, and may lead to many...

Cancer de la prostate localisé: une signature moléculaire pour identifier les tumeurs à faible risque de progression

Le cancer de la prostate est le cancer le plus fréquent chez l’homme. L‘ablation totale de la prostate, ou prostatectomie radicale, est le traitement de référence des cancers localisés de la prostate. Toutefois, cette intervention peut s’accompagner d’un...

Prochain Séminaire CIT le jeudi 7 juin 10h30 – Instabilité Microsatellitaire dans les Cancers

Notre prochain séminaire portera sur l’instabilité microsatellitaire dans les cancers. C’est une forme d’instabilité communément répandue dans de nombreux types de cancers, de 1 à 30% en fonction des types de cancers. Cette instabilité est due à une déficience...

Cancer du pancréas : l’analyse moléculaire des cellules tumorales et de leur microenvironnement a permis d’identifier une nouvelle thérapie

Des recherches menées par l’équipe Cartes d’Identité des Tumeurs (CIT)® de la Ligue en collaboration avec l’équipe labellisée de Juan Iovanna (Inserm 1068 – CNRS UMR 7258, Marseille) ont permis d’identifier et valider une nouvelle cible thérapeutique...

Immune Environnement Impacts the Prognosis of Colon Tumors

Research conducted in collaboration with Alex Duval's team (Inserm UMRS 938, Saint-Antoine Hospital Research Center, Paris) allowed us to better assess the impact of the tumor microenvironment on the prognosis of colorectal tumors. This work also may explain why...

CIT Program Search by cancer (in dev) 

CIT Program Research Cancer Tumeurs Ligue
CIT Program Research Cancer Tumeurs Ligue
CIT Program Research Cancer Tumeurs Ligue
CIT Program Research Cancer Tumeurs Ligue
CIT Program Research Cancer Tumeurs Ligue
CIT Program Research Cancer Tumeurs Ligue
CIT Program Research Cancer Tumeurs Ligue
CIT Program Research Cancer Tumeurs Ligue
CIT Program Research Cancer Tumeurs Ligue
CIT Program Research Cancer Tumeurs Ligue
CIT Program Research Cancer Tumeurs Ligue
CIT Program Research Cancer Tumeurs Ligue

CIT Team

Aurélien de Reyniès

Aurélien de Reyniès

Scientific Director, PhD

Computer scientist and statistician by training, Aurélien de Reyniès obtained a PhD from the University of Paris Dauphine in 2002. He then joined the League to found the bioinformatics team of the CIT program. Since 2014, he has been leading the CIT program, after having supervised the CIT bioinformatics team for 10 years.

Mira Ayadi

Mira Ayadi

Operational Director, PhD

Mira Ayadi joined the CIT program in 2013 as Operational Director, after a PhD in Molecular and Cellular Biology and 6 years of experience on technical platforms. She is in charge of the coordination of the CIT program.

Laetitia Marisa

Laetitia Marisa

Research Scientist, PhD

After a Master degree in molecular biology/physiology, Laetitia specialised in bioinformatics/biostatistics when genomics was emerging. Her expertise was acquired in Pasteur Institute, Center of Molecular Genetic and Curie Institute. She joined CIT program in 2007 and obtained her PhD with her work on genomics of colorectal cancer.

Sylvie Job

Sylvie Job

Research Scientist, PhD

Trained as a biologist, Sylvie Job moved on to an in silico biology PhD dedicated to modelling the gene networks. She joined the CIT program in 2011 after two post-doctoral stages in bioinformatics and biostatistics. She is currently specialized in the oncogenomics research on pheochromocytoma, cholangiocarcinoma, breast and kidney cancers.

Aurélie Kamoun

Aurélie Kamoun

Research Scientist, PhD

Aurélie graduated from Ecole des Ponts ParisTech, with a major in mathematics and computer science. She further studied computational biology at ETH Zürich, and obtained a PhD in cancer genomics by conducting research on bladder cancer at Institut Curie. She joined the CIT program in 2013

Rémy Nicolle

Rémy Nicolle

Research Scientist, PhD

After graduating in systems biology at the Paris-Saclay University, he obtained his Ph.D. at the Institut Curie studying the transcriptional dysregulations driving bladder cancer. He joined the CIT in 2015 to focus on the genomics of pancreatic cancer.

Yuna Blum

Yuna Blum

Research Scientist, PhD

Yuna has a PhD in Genetics/Applied Statistics. After a year as an associate professor in statistics at Agrocampus Ouest, she pursued her research on omics data integration as a postdoctoral fellow in the Medicine/Cardiology Department at UCLA (Los Angeles). She joined the CIT program in 2015.

Florent Petitprez

Florent Petitprez

Research Scientist, PhD

After graduating from Ecole polytechnique in bioinformatics and from AgroParisTech in biotechnologies, Florent focused on applied bioinformatics. He obtained his PhD in 2018 after his work at the CIT program and the Cordeliers Research Center on the clinical impact of the immune and stromal tumor microenvironment.

Sami Mahmoudi

Sami Mahmoudi

Linux System Engineer

Graduated in IT system & security from ECE Paris, Sami developed strong expertise in different private sector companies. He joined CIT program in 2018 and deployed a High Performance Cluster contributing to reduce processing time of genomic pipelines.

Lucile Armenoult

Lucile Armenoult

Engineer in Molecular Biology

Lucile Armenoult has a Master’s degree in Biotechnology validate by a work on cervical cancer at the Paterson Institute for Cancer Research (Manchester). She joined the Biological Ressources Platform of CIT Program in 2010 and is in charge of it since 2012.

Aurélia Baurès

Aurélia Baurès

Biology Research Assistant

After two-year technical degree in Bioanalyses and Controls, Aurélia Baurès has worked on the involvement of B and T lymphocytes on multiple sclerosis in a research team at the Necker Enfants Malades Institute. She joined the Biological Ressources Platform of CIT Program in 2018 through a collaboration with Inserm